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Research & Leadership

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More Research On Enamel Regeneration

Hi everyone! Last time I looked into regenerative dentistry it was pretty interesting so I found another article, this time on stem cells. The article explains how researchers look at how stems cells could be used to create cells similar to ameloblasts, which are the cells that produce tooth enamel. The issue is that humans don’t normally have active ameloblasts after teeth develop so enamel cannot regenerate naturally. With stem-cell-derived cells and a molecules that activates something called the Notch signaling pathway, researchers are able to encourage cells to mature into ameloblast-like cells which are able to produce an enamel-like material. It’s yet another way researchers are pushing to repair damaged teeth, so I thought it was pretty interesting. Definitely check it out!


https://pubmed.ncbi.nlm.nih.gov/41765949/

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This article makes me wonder and hope... Going back to the pulp therapy article you posted previously, if they can somehow find a way to regenerate a whole new tooth from stem cell regeneration of the enamel, dentin and pulp... You could possibly maybe perform immediate implantation of stem cell generated tooth after an extraction. You are literally replacing a old/broken tooth with a brand new one... A tooth transplant! Wouldn't that be something!!!

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