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Oral Cancers

Hi everyone, I was recently reminded about how a dentist I know was able to identify oral cancer in one of her patients and thankfully got her to seek medical attention before it was too late, so I decided to look more into what oral cancer exactly is.

Oral cancer is cancer that develops in the tissues of the mouth or nearby areas of the throat. This means that the lips, gums, tongue, inner cheeks, and floor or roof of the mouth are all potential sites where oral cancer can occur. Oropharyngeal cancers, cancers that occur in the tissues of the oropharynx, or the middle part of the throat behind the mouth, appear further back, such as at the base of the tongue or on the tonsils. Major risk factors include tobacco and alcohol consumption, with HPV as a big cause of oropharyngeal cancer. Other factors, such as UV exposure,…


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great post Gavin!!


a couple of thoughts about oral cancer:


Every time I’m at the dentist, they check under my tongue and throughout my mouth to make sure there isn’t a β€œsneaky” cancer developing. It’s one of those quick examinations that can be easy to take for granted, but it really highlights the importance of early detection.


The few cases of oral cancer I’ve encountered were peripheral to my workβ€”they were part of the medical histories of patients who were actually seeing me for their eye appointments. Unfortunately, the cases I saw were fairly dramatic. At least a couple of these patients had undergone extensive surgery, including procedures that appeared to involve removal of portions of the jaw, leaving significant changes to their appearance and speech.


As with so many health issues, early detection and being informed really matter.Β Knowing what to look for, can make a meaningful difference.


That seems to be the recurring theme of our BioImpact group: knowledge, awareness, and early action can have a real impact on outcomes.

More Research On Enamel Regeneration

Hi everyone! Last time I looked into regenerative dentistry it was pretty interesting so I found another article, this time on stem cells. The article explains how researchers look at how stems cells could be used to create cells similar to ameloblasts, which are the cells that produce tooth enamel. The issue is that humans don’t normally have active ameloblasts after teeth develop so enamel cannot regenerate naturally. With stem-cell-derived cells and a molecules that activates something called the Notch signaling pathway, researchers are able to encourage cells to mature into ameloblast-like cells which are able to produce an enamel-like material. It’s yet another way researchers are pushing to repair damaged teeth, so I thought it was pretty interesting. Definitely check it out!


https://pubmed.ncbi.nlm.nih.gov/41765949/

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This article makes me wonder and hope... Going back to the pulp therapy article you posted previously, if they can somehow find a way to regenerate a whole new tooth from stem cell regeneration of the enamel, dentin and pulp... You could possibly maybe perform immediate implantation of stem cell generated tooth after an extraction. You are literally replacing a old/broken tooth with a brand new one... A tooth transplant! Wouldn't that be something!!!

Osteoporosis

Hi guys! Since the case we saw on osteoporosis/osteonecrosis was so interesting, I decided to look further into the subject. According to this article, Osteoporosis in the jaw can occur due to delayed bone healing in consequence of some medications. As a result of this delayed healing, jaw infection, pain, and even bone rotting and prone to occur. To reduce risk of osteoporosis, the article says to maintain healthy oral hygiene and follow a well-balanced diet. It’s a very short read so definitely check it out!


https://www.csddentistry.com/2022/09/27/osteoporosis-and-its-complications-to-dental-health/

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Thanks for sharing this! I found it especially interesting that medications used to treat osteoporosis can sometimes contribute to serious complications in the jaw, which really highlights how interconnected medicine and dentistry are. It also emphasizes the importance of communication between physicians, dentists, and patients before procedures like tooth extractions. As our population ages, I think prevention through good oral hygiene, proper nutrition, and regular dental checkups will become even more important in reducing these risks.

Advancements in Regenerative Dentistry for Pulp Therapy

Hello everyone, I found a cool article that's related to the zoom meeting we had on Saturday about pulp! The article goes over vital pulp therapy and how preserving pulp could gradually change the way damaged teeth are treated. Rather than focusing solely on the current treatment methods like root canals or extractions, researchers are instead looking towards stem cells, growth factors, and biomaterials that could be used to help the tooth regenerate naturally. I just think it's amazing to see how these advancements can completely change the way we manage dental care! https://www.frontiersin.org/journals/dental-medicine/articles/10.3389/fdmed.2026.1857656/full

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This could save many patients from needing root canal treatments or extractions/implants. I may have mentioned this before, but I always tell the patents to save your own tooth if possible. Implants are a great option but your own tooth is still better in my opinion even if RCT and crown is needed. Now, imagine if they can find a way to regenerate dentin and enamel layer along with pulp and be readily available and affordable. It would be life changing for many people.

"Tooth in Eye Surgery"

Hi guys --

I remember studying this topic a while ago and realized the correlation between ophthalmology and dentistry; this surgery uses the cornea to restore vision with a likelihood of success. It's known as Osteo-Odonto Keratoprothesis.

Here's the article:

https://www.nature.com/articles/sj.bdj.2013.383

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This is one of the most fascinating examples of interdisciplinary medicine I’ve come across. πŸ˜… The fact that a patient’s own tooth can be used as part of a procedure to restore vision really demonstrates how interconnected different areas of healthcare are. It also makes me wonder what other tissues or structures we currently view as serving a single purpose could have unexpected applications in regenerative medicine. As fields like dentistry, ophthalmology, tissue engineering, and AI continue to converge, I think we’ll see even more innovative treatments that challenge our traditional understanding of medicine.

Dynamic Computer-Assisted Surgery (dCAS) in oral surgery

While touching on the subject I found another cool article related to dentistry! I think it’s really cool that technological advancements are working hand in hand with medical advancements to improve both of them simultaneously. This article shows an example of that where dCAS gives real time 3D guidence, kind of like a gps, assiting surgery to improve efficiency, accuracy, and saftey. It’s definitely a promising advancement you should check out!


https://www.mdpi.com/2077-0383/15/2/886

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One of the most compelling findings in this systematic review is what dCAS does for less experienced surgeons. Technology is literally closing the gap between a seasoned surgeon and someone earlier in their training. That has massive implications for patient safety and healthcare equity, especially in areas where access to highly experienced specialists is limited.


So what’s the catch? πŸ€”

Why does this matter for our BioImpact team?πŸ’‘


This is the perfect example of what we talk about when we say technology and medicine are evolving together. Whether you’re interested in dentistry, surgery, biomedical engineering, or healthcare policy- understanding how tools like dCAS are reshaping clinical practice is part of being a well-rounded, forward-thinking healthcare professional.


Keep bringing these gems - this is exactly the BioImpact energy we love! πŸ™Œ

Lab Grown Teeth, dental science

For those interested in dentistry and dental science, I found this article very interesting! While a fully functional replacement to human teeth still hasn’t been developed, early models and tooth-like structures are amazingly seeing promising success. It’s only about a 7 min read so it’s definitely something you should check out!


https://www.cnn.com/science/lab-grown-human-teeth-spc


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Thank you for the article Gavin. It would be life-changing for so many patients young and old if you can replace a missing tooth with your own biologically compatible tooth. I see many cases at my clinic where kids in elementary school ages extract their permanent first molars due to gross cavity (unrestorable), pain and/or infection. To answer the question below, even if this treatment option was available to the patients today, there are many facotrs patients consider before deciding on the final treatment plan. In my practice, one of the biggest deciding factor would be the out of pocket costs or whether their insurance would cover it. There are many patients that would rather extract their permanent tooth versus saving thier tooth if they have to pay out of pocket. Unfortunately this is the reality. Implants costs in the thousands now. I cannot imagine how much the lab grown tooth would be. I'm certain people would everything in their power to save their vital organs such as heart or brain. People have 32 teeth including wisdom teeth. Missing couple of molars are not life-alerting condition for many people. IF they can somehow make it affordable or same range as an implant, it would be a differenty story. Let's hope...

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